S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi
This study shows that S-acylation of NLRP3's Cys-130 residue regulates its Golgi association through a nigericin-sensitive cycle, linking Golgi dysfunction to NLRP3 activation.
bioRxiv · Nov 14, 2023Cell Biology