Author

L. Xian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Macho· 2 shared G. Yu· 2 shared A. K. Aragaki· 1 shared B. A. Johnson· 1 shared B. Wu· 1 shared C. Xu· 1 shared D. Dordai· 1 shared D. J. McConkey· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPlant Biology

A. Macho

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Adipokine C1q/Tumor necrosis factor-related protein 3 (CTRP3) Attenuates Intestinal Inflammation via Histone Deacetylase Sirtuin 1 (SIRT1)/NF-κB Signaling

H. Yu, Z. Zhang, G. Li, Y. Feng, L. Xian, F. J. Bakhsh, D. Xu, C. Xu, T. Vong, B. Wu, F. M. Selaru, F. Wan, G. W. Wong, M. Donowitz

This study shows that CTRP3 reduces intestinal inflammation in colitis models and IBD patients by modulating SIRT1/NF-κB signaling to suppress pro-inflammatory cytokines.

bioRxiv · May 8, 2022 · PreprintPathology

The indoleamine 2,3 dioxygenase pathway drives intratumoral B cell maintenance.

B. A. Johnson, A. K. Aragaki, D. M. Williams, O. Rogers, J. Mountain, L. Luo, W. Zhang, L. Xian, M. Feng, L. Chia, D. Dordai, N. M. Hahn, S. Desiderio, T. S. Johnson, D. J. McConkey, L. M. S. Resar

This study shows that inhibiting the IDO1 pathway reduces tumor-infiltrating B cells in melanoma models, suggesting potential therapeutic strategies for solid tumors.

bioRxiv · Aug 25, 2021 · PreprintImmunology

SGT1 is not required for bacterial PAMP-triggered immunity

G. Yu, L. Xian, H. Zhuang, A. Macho

This study shows that SGT1 is not required for bacterial PAMP-triggered immunity in Nicotiana benthamiana and Arabidopsis.

bioRxiv · May 8, 2020 · PreprintPlant Biology

A bacterial effector protein prevents MAPK-mediated phosphorylation of SGT1 to suppress plant immunity

G. Yu, L. Xian, H. Xue, W. Yu, J. Rufian, Y. Sang, R. Morcillo, Y. Wang, A. Macho

This study identifies RipAC, a bacterial effector that inhibits SGT1 phosphorylation by blocking its interaction with MAPKs, thereby suppressing plant immunity.

bioRxiv · Jan 24, 2020Plant Biology