Author

D. Mandrioli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 5

Signature Assays, Organisms & Methods

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Organism:rat· 5 Approach:experimental assay· 4 Assay:metagenomics· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

F. Belpoggi· 5 shared R. Mesnage· 5 shared L. Falcioni· 4 shared C. A. Mein· 3 shared E. Bourne· 3 shared M. Antoniou· 3 shared C. Amiel· 2 shared E. Savage· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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5 shared papersPharmacology & Toxicology

F. Belpoggi

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5 papers

Recent·Most cited

Leukemia in Sprague-Dawley Rats Exposed Long-term from Prenatal Life to Glyphosate and Glyphosate-Based Herbicides

S. Panzacchi, E. Tibaldi, L. De Angelis, L. Falcioni, F. Gnudi, M. Iuliani, M. Manservigi, F. Manservisi, I. Manzoli, I. Menghetti, R. Montella, R. Noferini, D. Sgargi, V. Strollo, M. Antoniou, , D. Mandrioli

This study shows that glyphosate and glyphosate-based herbicides caused increased leukemia incidence in rats at exposure levels within the EU ADI and NOAEL.

bioRxiv · Nov 14, 2023 · PreprintPharmacology & Toxicology

Glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal community composition in the rat caecum microbiome

R. Mesnage, S. Panzacchi, E. Bourne, C. A. Mein, M. Perry, J. Hu, J. Chen, D. Mandrioli, F. Belpoggi, M. N. Antoniou

This study shows that glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal communities in rat caecum microbiomes, with formulations causing more pronounced changes than glyphosate alone.

bioRxiv · Nov 19, 2021 · PreprintPharmacology & Toxicology

Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats

R. Mesnage, M. Ibragim, D. Mandrioli, L. Falcioni, E. Tibaldi, F. Belpoggi, I. Brandsma, E. Bourne, E. Savage, C. A. Mein, M. N. Antoniou

This study compares the genotoxicity of glyphosate and Roundup herbicides using stem cell assays and molecular profiling in rats, finding Roundup causes more carcinogenesis-related changes.

bioRxiv · Apr 12, 2021Pharmacology & Toxicology

Multi-omics phenotyping of the gut-liver axis allows health risk predictability from in vivo subchronic toxicity tests of a low-dose pesticide mixture

R. Mesnage, M. Teixeira, D. Mandrioli, L. Falcioni, Q. R. Ducarmon, R. D. Zwittink, C. Amiel, J.-M. Panoff, E. Bourne, E. Savage, C. A. Mein, F. Belpoggi, M. Antoniou

The paper uses multi-omics analysis on pesticide-exposed rats to show metabolic and epigenetic changes in the gut-liver axis that predict health risks not detected by standard tests.

bioRxiv · Aug 25, 2020 · PreprintPharmacology & Toxicology

Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

R. Mesnage, M. Teixeira, D. Mandrioli, L. Falcioni, Q. R. Ducarmon, R. D. Zwittink, C. Amiel, J.-M. Panoff, F. Belpoggi, M. Antoniou

This study shows glyphosate inhibits the shikimate pathway in rat gut microbiota, altering microbial communities and metabolites, with potential health implications.

bioRxiv · Dec 11, 2019Pharmacology & Toxicology