Author

L. Falcioni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:rat· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Assay:metabolomics· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. Mandrioli· 4 shared F. Belpoggi· 4 shared R. Mesnage· 4 shared M. Antoniou· 3 shared C. A. Mein· 2 shared C. Amiel· 2 shared E. Bourne· 2 shared E. Savage· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersPharmacology & Toxicology

D. Mandrioli

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Leukemia in Sprague-Dawley Rats Exposed Long-term from Prenatal Life to Glyphosate and Glyphosate-Based Herbicides

S. Panzacchi, E. Tibaldi, L. De Angelis, L. Falcioni, F. Gnudi, M. Iuliani, M. Manservigi, F. Manservisi, I. Manzoli, I. Menghetti, R. Montella, R. Noferini, D. Sgargi, V. Strollo, M. Antoniou, , D. Mandrioli

This study shows that glyphosate and glyphosate-based herbicides caused increased leukemia incidence in rats at exposure levels within the EU ADI and NOAEL.

bioRxiv · Nov 14, 2023 · PreprintPharmacology & Toxicology

Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats

R. Mesnage, M. Ibragim, D. Mandrioli, L. Falcioni, E. Tibaldi, F. Belpoggi, I. Brandsma, E. Bourne, E. Savage, C. A. Mein, M. N. Antoniou

This study compares the genotoxicity of glyphosate and Roundup herbicides using stem cell assays and molecular profiling in rats, finding Roundup causes more carcinogenesis-related changes.

bioRxiv · Apr 12, 2021Pharmacology & Toxicology

Recurrence quantification analysis of heart rate variability is a COVID-safe alternative to gas analysis in the detection of metabolic thresholds

G. Zimatore, L. Falcioni, M. Gallotta, V. Bonavolnta, M. Campanella, M. De Spirito, L. Guidetti, C. Baldari

This study shows that Recurrence Quantification Analysis of HRV can reliably detect metabolic thresholds without gas analysis, making it a safe alternative during the COVID-19 pandemic.

bioRxiv · Mar 22, 2021 · PreprintBiophysics

Multi-omics phenotyping of the gut-liver axis allows health risk predictability from in vivo subchronic toxicity tests of a low-dose pesticide mixture

R. Mesnage, M. Teixeira, D. Mandrioli, L. Falcioni, Q. R. Ducarmon, R. D. Zwittink, C. Amiel, J.-M. Panoff, E. Bourne, E. Savage, C. A. Mein, F. Belpoggi, M. Antoniou

The paper uses multi-omics analysis on pesticide-exposed rats to show metabolic and epigenetic changes in the gut-liver axis that predict health risks not detected by standard tests.

bioRxiv · Aug 25, 2020 · PreprintPharmacology & Toxicology

Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

R. Mesnage, M. Teixeira, D. Mandrioli, L. Falcioni, Q. R. Ducarmon, R. D. Zwittink, C. Amiel, J.-M. Panoff, F. Belpoggi, M. Antoniou

This study shows glyphosate inhibits the shikimate pathway in rat gut microbiota, altering microbial communities and metabolites, with potential health implications.

bioRxiv · Dec 11, 2019Pharmacology & Toxicology