Multi-omics phenotyping of the gut-liver axis allows health risk predictability from in vivo subchronic toxicity tests of a low-dose pesticide mixture
R. Mesnage, M. Teixeira, D. Mandrioli, L. Falcioni, Q. R. Ducarmon, R. D. Zwittink, C. Amiel, J.-M. Panoff, E. Bourne, E. Savage, C. A. Mein, F. Belpoggi, M. Antoniou
The paper uses multi-omics analysis on pesticide-exposed rats to show metabolic and epigenetic changes in the gut-liver axis that predict health risks not detected by standard tests.
bioRxiv · Aug 25, 2020 · PreprintPharmacology & Toxicology