Author

D. N. Kenanova

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Biochemistry· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Ottmann· 1 shared E. J. Visser· 1 shared E. Sijbesma· 1 shared F. Centorrino· 1 shared H. R. Vickery· 1 shared J. M. Virta· 1 shared J. R. Neitz· 1 shared L. Brunsveld· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

C. Ottmann

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1 paper

Recent·Most cited

A Systematic Approach to the Discovery of Protein-Protein Inter-action Stabilizers

D. N. Kenanova, E. J. Visser, J. M. Virta, E. Sijbesma, F. Centorrino, H. R. Vickery, M. Zhong, J. R. Neitz, L. Brunsveld, C. Ottmann, M. R. Arkin

This study uses disulfide tethering to identify small molecule stabilizers of 14-3-3{sigma} phospho-peptide interactions, finding selective and efficacious fragments for four of five client complexes.

bioRxiv · Jan 29, 2023 · PreprintBiochemistry