Author

E. J. Visser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Ottmann· 2 shared L. Brunsveld· 2 shared D. K. Scott· 1 shared D. N. Kenanova· 1 shared E. Sijbesma· 1 shared F. Centorrino· 1 shared H. R. Vickery· 1 shared I. L. Tse· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

C. Ottmann

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2 papers

Recent·Most cited

Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.

L. S. Katz, E. J. Visser, K. F. Plitzko, M. Pennings, P. J. Cossar, I. L. Tse, M. Kaiser, L. Brunsveld, C. Ottmann, D. K. Scott

This paper identifies molecular glues that stabilize the ChREBP/14-3-3 complex, protecting beta cells from glucolipotoxicity by preventing ChREBP-mediated dedifferentiation.

bioRxiv · Feb 16, 2024Cell Biology

A Systematic Approach to the Discovery of Protein-Protein Inter-action Stabilizers

D. N. Kenanova, E. J. Visser, J. M. Virta, E. Sijbesma, F. Centorrino, H. R. Vickery, M. Zhong, J. R. Neitz, L. Brunsveld, C. Ottmann, M. R. Arkin

This study uses disulfide tethering to identify small molecule stabilizers of 14-3-3{sigma} phospho-peptide interactions, finding selective and efficacious fragments for four of five client complexes.

bioRxiv · Jan 29, 2023 · PreprintBiochemistry