Author

D. Nijhawan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. A. Posner· 1 shared B. Wang· 1 shared C. Huerta· 1 shared C. L. Cervantes· 1 shared D. G. McFadden· 1 shared E. Lin· 1 shared E. Morton· 1 shared E. Wallace· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

B. A. Posner

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2 papers

Recent·Most cited

Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules

T. P. Nguyen, M. Fang, J. Kim, B. Wang, E. Lin, V. Khivansara, N. Barrows, G. Rivera-Cancel, M. Goralski, C. L. Cervantes, S. Xie, J. M. Peterson, J. M. Povedano, M. I. Antczak, B. A. Posner, , D. Nijhawan

This study develops an inducible mismatch repair system to identify targets of orphan cytotoxins by screening for compound resistance mutations in engineered cell lines.

bioRxiv · Feb 21, 2023Biochemistry

Structural basis of recruitment of RBM39 to DCAF15 by a sulfonamide molecular glue E7820

X. Du, O. A. Volkov, R. Czerwinski, H. Tan, C. Huerta, E. Morton, J. Rizzi, P. Wehn, R. Xu, D. Nijhawan, E. Wallace

The paper investigates how E7820 recruits RBM39 to the DCAF15 E3 ligase complex through structural and kinetic analysis, revealing its mechanism as a molecular glue.

bioRxiv · Sep 5, 2019Biophysics