Non-canonical Activation of Human Group 2 Innate Lymphoid Cells by TLR4 Signaling
L. She, H. H. Alanazi, J. Wang, D. P. Chupp, Y. Xu, H. Zan, Z. Xu, Y. Sun, N. Xiong, N. Zhang, X. Zhang, Y. Liu, X.-D. Li
This study shows that human ILC2 cells can be activated by TLR4 signaling through LPS, leading to cytokine production and B cell activation, distinct from classical IL-33 activation.
bioRxiv · Oct 29, 2020 · PreprintImmunology