The human small intestine contains two subsets of regulatory Foxp3+ CD4+ T cells with very different life span and functional properties.
S. K. Chauhan, R. B. Casado, O. J. B. Landsverk, H. Johannessen, D. Phung, F. Saetre, J. Jahnsen, R. Horneland, S. Yaqub, E. M. Aandahl, K. E. A. Lundin, E. S. Baekkevold, F. L. Jahnsen
This study identifies two distinct subsets of Foxp3+ CD4+ Tregs in the human small intestine with different functional properties and lifespans, which expand in celiac disease.
bioRxiv · Feb 12, 2020 · PreprintImmunology