Author

J. Jahnsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 8

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Research Focus:cell type annotation· 8 Organism:human· 8 Approach:experimental assay· 7 Research Focus:differential expression· 4 Assay:proteomics· 4 Assay:flow cytometry· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. E. A. Lundin· 5 shared L. M. Sollid· 5 shared R. Iversen· 4 shared C. Zhou· 2 shared F. L. Jahnsen· 2 shared I. Lindeman· 2 shared L. S. Hoydahl· 2 shared S. Yaqub· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersImmunology

K. E. A. Lundin

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Author profile →

8 papers

Recent·Most cited

Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease

I. Lindeman, L. S. Hoydahl, A. Christophersen, L. F. Risnes, J. Jahnsen, K. E. A. Lundin, L. M. Sollid, R. Iversen

The paper identifies circulating TG2-specific IgA cells in celiac disease patients, showing they are clonally related to intestinal plasma cells and generated via an extrafollicular response involving gluten-specific CD4+ T cells.

bioRxiv · Oct 20, 2023Immunology

Separate Gut Plasma Cell Populations Produce Autoantibodies Against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis

S. Das, J. Stamnaes, E. Kemppainen, K. Hervonen, K. E. A. Lundin, N. Parmar, F. L. Jahnsen, J. Jahnsen, K. Lindfors, T. Salmi, R. Iversen, L. M. Sollid

The paper identifies separate gut plasma cell populations in DH patients producing autoantibodies specific to TG2 and TG3 with no cross-reactivity.

bioRxiv · May 31, 2023Immunology

Antibodies to native gluten arise from cross-reactive B cells with implications for epitope spreading in celiac disease

C. Zhou, T. Osterbye, S. Dahal-Koirala, O. Steinsbo, J. Jahnsen, K. E. A. Lundin, S. Buus, L. M. Sollid, R. Iversen

The paper identifies a new native gluten epitope recognized by cross-reactive B cells in celiac disease, which may contribute to epitope spreading.

bioRxiv · Jan 29, 2022Immunology

Affinity-engineered human antibodies detect celiac disease gluten pMHC complexes and inhibit T-cell activation

R. Frick, L. S. Hoydahl, I. Hodnebrug, S. Kumari, G. Berntsen, J. R. Jeliazkov, K. S. Gunnarsen, T. Frigstad, E. S. Vik, K. E. A. Lundin, S. Yaqub, J. Jahnsen, J. J. Gray, L. M. Sollid, I. Sandlie, G. A. Loset

The paper describes the engineering of high-affinity human antibodies that recognize gluten epitopes bound to HLA-DQ2.5 and inhibit T-cell activation in celiac disease.

Science Immunology · Aug 10, 2021Peer-reviewedImmunology

Serum proteomic profiling at diagnosis predicts clinical course, and need for intensification of treatment in inflammatory bowel disease.

R. Kalla, A. T. Adams, D. Bergemalm, S. Vatn, N. A. Kennedy, P. Ricanek, J. C. Lindstrom, A. Ocklind, F. Hjelm, N. T. Ventham, G.-T. Ho, C. Petren, IBD Character Consortium, D. Repsilber, J. D. Soderholm, , J. Satsangi

This study identifies a serum protein panel that distinguishes inflammatory bowel disease from non-IBD controls and predicts treatment escalation.

bioRxiv · Aug 31, 2020Immunology

Longevity, clonal relationship and transcriptional program of celiac disease-specific plasma cells

I. Lindeman, C. Zhou, L. M. Eggesbo, Z. Miao, J. Polak, K. E. Lundin, J. Jahnsen, S.-W. Qiao, R. Iversen, L. M. Sollid

The paper analyzes single-cell RNA-seq data from plasma cells in celiac disease patients to identify transcriptional differences and clonal relationships between disease-specific and non-specific plasma cells.

bioRxiv · Apr 30, 2020Immunology

The human small intestine contains two subsets of regulatory Foxp3+ CD4+ T cells with very different life span and functional properties.

S. K. Chauhan, R. B. Casado, O. J. B. Landsverk, H. Johannessen, D. Phung, F. Saetre, J. Jahnsen, R. Horneland, S. Yaqub, E. M. Aandahl, K. E. A. Lundin, E. S. Baekkevold, F. L. Jahnsen

This study identifies two distinct subsets of Foxp3+ CD4+ Tregs in the human small intestine with different functional properties and lifespans, which expand in celiac disease.

bioRxiv · Feb 12, 2020 · PreprintImmunology

Single cell transcriptome atlas of immune cells in human small intestine and in celiac disease

H. Stunnenberg, N. Atlasy, A. Bujko, P. B. Brazda, E. Janssen-Megens, E. S. Bakkenvold, J. Jahnsen, F. Jahsen

This study uses single-cell RNA-sequencing to analyze immune cell heterogeneity in human small intestine and celiac disease, revealing significant changes in myeloid, T cell, and NK-T-like cell populations.

bioRxiv · Aug 1, 2019Immunology