Author

D. R. Plas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. Meller· 3 shared M. E. Bischoff· 3 shared D. Secic· 2 shared J. Biesiada· 2 shared M. F. Czyzyk-Krzeska· 2 shared A. D. Price· 1 shared A. D'Alessandro· 1 shared A. Martines· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

J. Meller

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3 papers

Recent·Most cited

Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma

M. Czyzyk-Krzeska, M. E. Bischoff, B. Shamsaei, J. Yang, D. Secic, B. Vemuri, J. A. Reisz, A. D'Alessandro, C. Bartolacci, R. Adamczyk, L. Schmidt, J. Wang, A. Martines, J. Biesiada, K. E. Vest, , J. T. Cunningham

This study shows copper drives metabolic remodeling and progression in clear cell renal cell carcinoma by coordinating bioenergy, biosynthesis, and redox homeostasis.

bioRxiv · Jan 16, 2024Cancer Biology

MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells

R. Verma, P. Aggarwal, J. Reigle, D. Secic, M. F. Czyzyk-Krzeska, C. Wetzel, M. E. Bischoff, K. VandenHeuvel, J. Biesiada, B. Ehmer, J. A. Landero Figueroa, D. R. Plas, M. Medvedovic, J. Meller

This study shows that MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells, affecting tumor initiation and epigenetic remodeling.

bioRxiv · May 11, 2022 · PreprintCell Biology

Selective MAP1LC3C (LC3C) autophagy requires noncanonical initiation regulators and the paralog-specific C-terminal peptide

M. F. Czyzyk-Krzeska, M. E. Bischoff, Y. Zang, J. Chou, A. D. Price, N. J. Talbot, M. J. Newbold, A. Paul, J.-L. Guan, D. R. Plas, J. Meller

This study identifies noncanonical regulators and a C-terminal peptide essential for LC3C-mediated selective autophagy targeting PDMBs in cancer stem cells.

bioRxiv · Feb 19, 2021Cancer Biology