R. Verma

TFIIS is required for reproductive development and thermal adaptation in barley

This study shows TFIIS is essential for reproductive development and heat stress survival in barley, with molecular mechanisms involving delayed heat stress protein expression and proteotoxicity.

Bridging fungal resistance and plant growth through constitutive overexpression of Thchit42 gene in Pelargonium graveolens

This study overexpresses the Thchit42 gene in Pelargonium graveolens to enhance fungal resistance and plant growth, showing increased leaf size and oil content.

The Implant-Induced Foreign Body Response is Limited by CD13-Dependent Regulation of Ubiquitination of Fusogenic Proteins

This study shows CD13 regulates macrophage fusion by controlling ubiquitination of fusogenic proteins, limiting foreign body response fibrosis and suggesting CD13 as a therapeutic target.

Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15

The paper identifies TFEB regulation of BMP lipid catabolism via Pla2g15, showing increased BMP lipids in Pla2g15 knockout mice and cold intolerance upon TFEB knockdown.

The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics

This study investigates the cellular effects of the PNPLA3-I148M variant, revealing its role in altering lipid droplet-Golgi dynamics and inducing proteomic and transcriptomic changes associated with liver disease.

CrOssing fiber Modeling in the Peritumoral Area using dMRI (COMPARI)

This paper introduces COMPARI, a new multi-compartment model for dMRI that improves fiber tract visualization in brain tumor peritumoral regions by removing isotropic components like free water.

A chromosome-scale assembly of Brassica carinata (BBCC) accession HC20 containing resistance to multiple pathogens and an early generation assessment of introgressions into B. juncea (AABB)

The paper presents a chromosome-scale genome assembly of B. carinata and assesses introgression potential into B. juncea for disease resistance.

Human endogenous retrovirus-R envelope is a host restriction factor against severe acute respiratory syndrome-coronavirus-2

The paper identifies HERV-R envelope as a host restriction factor that inhibits SARS-CoV-2 replication through ERK and p38 MAPK signaling.

MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells

This study shows that MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells, affecting tumor initiation and epigenetic remodeling.

RNA-protein interactome at the Hepatitis E virus internal ribosome entry site

This study identifies the RNA-protein interactome of the Hepatitis E virus IRESl element and confirms its function as a bona fide internal ribosome entry site.

SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19

This study shows SARS-CoV-2 infects human adipose tissue, causing inflammation linked to severe COVID-19 outcomes in obese individuals.

Targeting of Cdc42 GTPase in regulatory T cells unleashes anti-tumor T cell immunity

This study shows that targeting Cdc42 in regulatory T cells promotes anti-tumor immunity without causing autoimmunity by inducing Treg plasticity and altering pH through carbonic anhydrase I.

Computational modeling of C-terminal tails to predict the calcium-dependent secretion of ER resident proteins

The paper develops a computational method to predict ER retention sequences that can undergo secretion during ER calcium depletion by analyzing non-canonical ERS sequences.

Fine-tuning the transcriptional regulatory model of adaptation response to phosphate stress in maize (Zea mays L.)

This study identifies Pi-responsive genes in maize and proposes an updated transcriptional regulatory model for Pi starvation response.

RNA-protein interaction analysis of SARS-CoV-2 5'- and 3'-untranslated regions identifies an antiviral role of lysosome-associated membrane protein-2

This study identifies host proteins interacting with SARS-CoV-2 5' and 3' UTRs, revealing Lamp2a's antiviral role by reducing viral RNA levels.

Injectable hydrogels for sustained co-delivery of subunit vaccines enhance humoral immunity

This paper introduces an injectable hydrogel platform for sustained co-delivery of subunit vaccines, which enhances humoral immunity by improving antigen and adjuvant presentation over time.

Single-cell RNA-seq reveals spatially restricted multicellular fibrotic niches during lung fibrosis

The paper identifies monocyte-derived alveolar macrophages as causally linked to fibrosis in lung tissue through autocrine signaling and fibroblast activation.

Freewater EstimatoR using iNtErpolated iniTialization (FERNET): Toward Accurate Estimation of Free Water in Peritumoral Region Using Single-Shell Diffusion MRI Data

FERNET improves free water estimation in peritumoral regions using single-shell diffusion MRI data, enhancing tractography in brain tumor patients.

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

The paper identifies a modular transcriptional signature for active tuberculosis that distinguishes it from latent infection and other diseases, showing dynamic heterogeneity in tuberculosis contacts.