Author

D. R. Wahl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. A. Lyssiotis· 2 shared K. Wilder-Romans· 2 shared A. C. Kimmelman· 1 shared A. J. Scott· 1 shared A. L. Elaimy· 1 shared A. Lin· 1 shared A. Myers· 1 shared A. Obrien· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

C. A. Lyssiotis

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2 papers

Recent·Most cited

GTP signaling links metabolism, DNA repair, and responses to genotoxic stress

W. Zhou, Z. Zhao, A. Lin, J. Yang, J. Xu, K. Wilder-Romans, A. Yang, J. Li, S. Solanki, J. Speth, N. Walker, A. J. Scott, A. U. Kothari, Y. Yao, E. R. Peterson, , D. R. Wahl

This study identifies a GTP-mediated signaling pathway linking metabolism to DNA repair and resistance to genotoxic stress in glioblastoma and non-malignant cells.

bioRxiv · Apr 12, 2023Cancer Biology

Tissue of Origin Dictates GOT1 Dependence and Confers Synthetic Lethality to Radiotherapy

B. S. Nelson, L. Lin, D. M. Kremer, C. M. Sousa, C. Cotta-Ramusino, A. Myers, J. Ramos, T. Gao, I. Kovalenko, K. Wilder-Romans, J. Dresser, M. Davis, H.-J. Lee, Z. C. Nwosu, S. Campit, , C. A. Lyssiotis

The paper shows that pancreatic ductal adenocarcinoma (PDA) is more dependent on GOT1 than colorectal cancer (CRC) and that GOT1 inhibition synergizes with radiotherapy to inhibit PDA growth.

bioRxiv · Jul 25, 2019Cancer Biology