A. Myers

Analysis of cell death induction by the barley NLR immune receptor PBR1

This study investigates PBR1-mediated cell death in barley by showing that full-length PBR1 is required for hypersensitive response and that self-association occurs independently of AvrPphB.

Candidate effector proteins from the maize tar spot pathogen Phyllachora maydis localize to diverse plant cell compartments

The paper identifies subcellular localization of effector proteins from the maize pathogen Phyllachora maydis using fluorescent tagging and microscopy.

Therapeutic targeting of differentiation state-dependent metabolic vulnerabilities in DIPG

This study identifies metabolic vulnerabilities in DIPG subtypes and shows that targeting these vulnerabilities with specific drugs can extend survival in preclinical models.

Synthetic oxepanoprolinamide iboxamycin is highly active against human pathogen Listeria monocytogenes

This study shows synthetic iboxamycin is effective against Listeria monocytogenes, overcoming resistance mechanisms, and highlights potential resistance development.

Mucosal and systemic responses to SARS-CoV-2 vaccination in infection naive and experienced individuals

This study examines immune responses to SARS-CoV-2 vaccination in individuals with and without prior infection, finding higher antibody levels and neutralizing titers in previously infected individuals.

Targeting the Cx26/NANOG/Focal Adhesion Kinase Complex via Cell Penetrating Peptides in Triple Negative Breast Cancers

This study demonstrates that a cell-penetrating peptide targeting the Cx26/NANOG/FAK complex inhibits tumor growth and alters NANOG activity in triple-negative breast cancer.

Symbiotic bacterial community of Drosophila melanogaster changes with nutritional modifications of the diet but can alleviate negative effects on larval phenotypes

This study shows that dietary changes in Drosophila melanogaster alter their gut microbiota composition and can be mitigated by symbiotic bacteria, improving larval survival and reducing triglyceride levels.

Septins regulate border cell shape and surface geometry downstream of Rho

This study shows that septins regulate border cell shape and surface geometry downstream of Rho in Drosophila, independent of myosin.

Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control

The paper identifies cellular and temporal factors associated with bacterial control in tuberculosis granulomas using multimodal data.

Influence of the lab adopted natural diet and environmental and parental microbiota on life history and metabolic phenotype of Drosophila melanogaster larvae.

This study examines how natural diet, environmental, and parental microbiota influence obesity-related traits in Drosophila larvae, showing significant differences in phenotypes based on diet and microbial exposure.

Engineering 6-phosphogluconate dehydrogenase to improve heat tolerance in maize seed development

This study improves maize heat tolerance by engineering heat-stable 6PGDH isozymes to function in amyloplasts, increasing kernel number under high nighttime temperatures.

GOT1 Inhibition Primes Pancreatic Cancer for Ferroptosis through the Autophagic Release of Labile Iron

This study shows that inhibiting GOT1 in pancreatic cancer primes cells for ferroptosis by promoting autophagy-mediated release of labile iron.

Tissue of Origin Dictates GOT1 Dependence and Confers Synthetic Lethality to Radiotherapy

The paper shows that pancreatic ductal adenocarcinoma (PDA) is more dependent on GOT1 than colorectal cancer (CRC) and that GOT1 inhibition synergizes with radiotherapy to inhibit PDA growth.

Maize defective kernel5 is a bacterial tamB homolog required for chloroplast envelope biogenesis

This study identifies DEK5 as a homolog of bacterial TamB required for chloroplast envelope biogenesis and metabolite transport in maize.

Thermally moderated firefly activity is delayed by precipitation extremes

The study examines how temperature and precipitation interact to influence firefly activity timing across different plant communities over 12 years.