D. R. Williams

Targeting phosphatase DUSP22 ameliorates skeletal muscle wasting via Akt independent JNK-FOXO3a repression

This study identifies DUSP22 as a novel target for preventing skeletal muscle wasting by repressing the JNK-FOXO3a pathway independently of Akt.

Real-time PCR detection of mixed Plasmodium ovale curtisi and wallikeri species infections in human and mosquito hosts

The paper develops a real-time PCR method to detect mixed Plasmodium ovale curtisi and wallikeri infections in humans and mosquitoes, revealing common co-infections and co-transmission.

Intracytoplasmic membranes develop in Geobacter sulfurreducens under thermodynamically limiting conditions

This study identifies intracytoplasmic membranes (ICMs) in Geobacter sulfurreducens under thermodynamically limiting conditions and links their presence to increased respiratory protein abundance.

Dynamic Changes in Fecal Bacterial Microbiota of Dairy Cattle across the Production Line

This study characterizes fecal bacterial communities in dairy cattle across different management units, finding dynamic changes in diversity and composition.

Inhibiting 5-lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signaling and insulin-like growth factor-1

This study shows that inhibiting 5-lipoxygenase with malotilate prevents skeletal muscle atrophy by enhancing organogenesis signaling and insulin-like growth factor-1 expression.

Divergence in dimerization and activity of primate APOBEC3C

This study identifies the molecular basis for differences in dimerization and antiviral activity of primate APOBEC3C proteins through biochemical, virological, and computational analyses.

Poor availability of context-specific evidence hampers decision-making in conservation

The paper assesses the availability of context-specific evidence for amphibian and bird conservation, finding it extremely low and unevenly distributed.

The challenge of heterogeneous evidence in conservation

This paper assesses biases and gaps in conservation literature for amphibians and birds, highlighting geographic and taxonomic disparities in study coverage and effectiveness metrics.