Author

D. S. Chandler

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

D. F. Comiskey· 1 shared M. Montes· 1 shared R. K. Singh· 1 shared S. Khurshid· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

D. F. Comiskey

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1 paper

Recent·Most cited

SRSF2 regulation of MDM2 reveals splicing as a therapeutic vulnerability of the p53 pathway

D. F. Comiskey, M. Montes, S. Khurshid, R. K. Singh, D. S. Chandler

This study shows that SRSF2 regulates MDM2 splicing, affecting p53 activity, and suggests splicing modulation as a potential therapeutic strategy for cancer.

bioRxiv · Sep 26, 2019Cancer Biology