Author

M. Montes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. F. Comiskey· 2 shared S. Khurshid· 2 shared A. Amadoz· 1 shared A. Zeida· 1 shared B. Shane· 1 shared C. Brown· 1 shared D. Chandler· 1 shared D. S. Chandler· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

D. F. Comiskey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A lncRNA-mediated metabolic rewiring of cell senescence

E. Grossi, F. P. Marchese, J. Gonzalez, E. Goni, J. M. Fernandez-Justel, A. Amadoz, N. Herranz, L. Puchades-Carrasco, M. Montes, M. Huarte

This study identifies sin-lncRNA, a long non-coding RNA that regulates mitochondrial metabolism during cellular senescence by modulating oxidative phosphorylation and DLST localization.

bioRxiv · Jan 25, 2024Cell Biology

Splice-switching of the insulin receptor in rhabdomyosarcoma: Rescuing the IR-B isoform for better treatment options.

S. Khurshid, M. Montes, D. F. Comiskey, B. Shane, E. Matsa, C. Brown, H. K. Bid, R. Wang, P. Houghton, F. Rigo, D. Chandler

This study shows that RMS tumors express more IR-A than IR-B, and reducing IR-A with SSOs decreases tumor growth by restoring IR-B expression.

bioRxiv · Oct 2, 2020 · PreprintCancer Biology

Exploring the Conformational Transition Between the Fully Folded and Locally Unfolded Substates of the Escherichia coli Thiol Peroxidase

D. S. Vazquez, A. Zeida, W. A. Agudelo, M. Montes, G. Ferrer-Sueta, J. Santos

This study investigates the conformational transition between fully folded and locally unfolded states of Escherichia coli thiol peroxidase using molecular dynamics simulations and identifies energy barriers and mutant effects on the transition.

bioRxiv · Dec 26, 2019Biophysics

SRSF2 regulation of MDM2 reveals splicing as a therapeutic vulnerability of the p53 pathway

D. F. Comiskey, M. Montes, S. Khurshid, R. K. Singh, D. S. Chandler

This study shows that SRSF2 regulates MDM2 splicing, affecting p53 activity, and suggests splicing modulation as a potential therapeutic strategy for cancer.

bioRxiv · Sep 26, 2019Cancer Biology