Strain-level differences in gut microbiome composition determine fecal IgA levels and are modifiable by gut microbiota manipulation
C. Yang, I. Mogno, E. J. Contijoch, J. N. Borgerding, V. Aggarwala, S. Y. Siu, Z. Li, E. K. Grasset, D. S. Helmus, M. C. Dubinsky, S. Mehandru, A. Cerutti, J. J. Faith
The paper identifies Bacteroides ovatus strains that induce IgA production and shows that manipulating these strains can modify gut IgA levels in mice.
bioRxiv · Aug 22, 2019Immunology