Author

M. C. Dubinsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:metagenomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

J. J. Faith· 3 shared V. Aggarwala· 3 shared A. Grinspan· 2 shared E. J. Contijoch· 2 shared I. Mogno· 2 shared J.-F. Colombel· 2 shared S. Mehandru· 2 shared S. Paramsothy· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersImmunology

J. J. Faith

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Gut microbiota bacterial strain richness is species specific and limits therapeutic engraftment

A. Chen-Liaw, V. Aggarwala, I. Mogno, C. Haifer, J. Eggers, Z. Li, D. Helmus, A. Hart, J. Wehkamp, E. Lamouse-Smith, R. L. Kerby, F. E. Rey, J. F. Colombel, M. Kamm, T. J. Borody, , J. J. Faith

The paper determines strain richness of common gut species and finds it is species-specific and limited in the gut, with temporary increases from therapeutic administration.

bioRxiv · Nov 1, 2022 · PreprintMicrobiology

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease

M. Suarez-Farinas, M. Tokuyama, G. Wei, R. Huang, A. Livanos, D. Jha, A. Levescot, H. Irizar, R. Kosoy, S. Cording, W. Wang, H. Irizar, R. Ungaro, A. Di Narzo, G. Martinez-Delgado, , S. Mehandru

The paper examines how intestinal inflammation affects ACE2 and TMPRSS2 expression and identifies shared molecular networks between COVID-19 and IBD.

bioRxiv · May 21, 2020Immunology

Defined microbiota transplant restores Th17/RORtγ+ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

G. J. Britton, E. J. Contijoch, M. P. Spindler, V. Aggarwala, G. Bongers, L. San Mateo, A. Baltus, A. Das, D. Gevers, T. J. Borody, N. O. Kaakoush, M. A. Kamm, H. Mitchell, S. Paramsothy, J. C. Clemente, , J. J. Faith

The paper shows that transplanting healthy microbiota into mice with IBD microbiotas restores Th17/RORγt+ regulatory T cell balance by reducing pathogenic strains.

bioRxiv · Nov 16, 2019Immunology

Strain-level differences in gut microbiome composition determine fecal IgA levels and are modifiable by gut microbiota manipulation

C. Yang, I. Mogno, E. J. Contijoch, J. N. Borgerding, V. Aggarwala, S. Y. Siu, Z. Li, E. K. Grasset, D. S. Helmus, M. C. Dubinsky, S. Mehandru, A. Cerutti, J. J. Faith

The paper identifies Bacteroides ovatus strains that induce IgA production and shows that manipulating these strains can modify gut IgA levels in mice.

bioRxiv · Aug 22, 2019Immunology