Author

V. Aggarwala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:metagenomics· 4 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

J. J. Faith· 5 shared I. Mogno· 4 shared A. Grinspan· 3 shared M. C. Dubinsky· 3 shared S. Paramsothy· 3 shared Z. Li· 3 shared A. Chen-Liaw· 2 shared C. Yang· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

J. J. Faith

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Gut microbiota bacterial strain richness is species specific and limits therapeutic engraftment

A. Chen-Liaw, V. Aggarwala, I. Mogno, C. Haifer, J. Eggers, Z. Li, D. Helmus, A. Hart, J. Wehkamp, E. Lamouse-Smith, R. L. Kerby, F. E. Rey, J. F. Colombel, M. Kamm, T. J. Borody, , J. J. Faith

The paper determines strain richness of common gut species and finds it is species-specific and limited in the gut, with temporary increases from therapeutic administration.

bioRxiv · Nov 1, 2022 · PreprintMicrobiology

Strain population structure varies widely across bacterial species and predicts strain colonization in unrelated individuals

J. J. Faith, A. Chen Liaw, V. Aggarwala, N. O. Kaakoush, T. Borody, H. Mitchell, M. A. Kamm, S. Paramsothy, E. S. Snitkin, I. Mogno

The study quantifies strain population sizes across bacterial species and finds prevalent strains in common gut microbiota are more likely to be shared among unrelated individuals.

bioRxiv · Oct 17, 2020 · PreprintMicrobiology

Quantification of discrete gut bacterial strains following fecal transplantation for recurrent Clostridioides difficile infection demonstrates long-term stable engraftment in non-relapsing recipients

V. Aggarwala, I. Mogno, Z. Li, C. Yang, G. J. Britton, A. Chen-Liaw, J. Mitcham, G. Bongers, D. Gevers, J. C. Clemente, J.-F. Colombel, A. Grinspan, J. J. Faith

The paper quantifies bacterial strain engraftment after FMT for rCDI and shows long-term stability in non-relapsing recipients, linking strain presence to clinical outcomes.

bioRxiv · Sep 10, 2020 · PreprintImmunology

Defined microbiota transplant restores Th17/RORtγ+ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

G. J. Britton, E. J. Contijoch, M. P. Spindler, V. Aggarwala, G. Bongers, L. San Mateo, A. Baltus, A. Das, D. Gevers, T. J. Borody, N. O. Kaakoush, M. A. Kamm, H. Mitchell, S. Paramsothy, J. C. Clemente, , J. J. Faith

The paper shows that transplanting healthy microbiota into mice with IBD microbiotas restores Th17/RORγt+ regulatory T cell balance by reducing pathogenic strains.

bioRxiv · Nov 16, 2019Immunology

Strain-level differences in gut microbiome composition determine fecal IgA levels and are modifiable by gut microbiota manipulation

C. Yang, I. Mogno, E. J. Contijoch, J. N. Borgerding, V. Aggarwala, S. Y. Siu, Z. Li, E. K. Grasset, D. S. Helmus, M. C. Dubinsky, S. Mehandru, A. Cerutti, J. J. Faith

The paper identifies Bacteroides ovatus strains that induce IgA production and shows that manipulating these strains can modify gut IgA levels in mice.

bioRxiv · Aug 22, 2019Immunology