Author

A. M. Blagborough

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 3 Organism:plant (other)· 3 Assay:proteomics· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

F. Angrisano· 3 shared K. A. Sala· 3 shared G. K. Christophides· 2 shared S. Tapanelli· 2 shared A. DeCosta· 1 shared A. El-Turabi· 1 shared A. Jaye· 1 shared A. M. Salman· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

F. Angrisano

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Effects of the G-quadruplex-binding drugs Quarfloxin and CX-5461 on the malaria parasite Plasmodium falciparum

H. M. Craven, G. Nettesheim, P. Cicuta, A. M. Blagborough, C. J. Merrick

This study investigates the effects of G-quadruplex-binding drugs quarfloxin and CX-5461 on Plasmodium falciparum, showing differing mechanisms of action and antimalarial efficacy.

bioRxiv · Jul 13, 2023 · PreprintMicrobiology

Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2

J. Feng, X. Dong, A. DeCosta, Y. Su, F. Angrisano, K. A. Sala, A. M. Blagborough, C. Lu, T. A. Springer

The paper reports monoclonal antibodies against Plasmodium berghei HAP2 and their crystal structures, showing how they block malaria transmission.

bioRxiv · Oct 22, 2021Immunology

Dissection-independent production of a protective whole-sporozoite malaria vaccine

J. Blight, K. A. Sala, E. Atcheson, H. Kramer, A. El-Turabi, E. Real, F. A. Dahalan, P. Bettencourt, E. Dickinson, E. Alves, A. M. Salman, C. J. Janse, F. Ashcroft, A. V. S. Hill, A. Reyes-Sandoval, , J. Baum

A four-step process isolates pure malaria sporozoites from mosquitoes without manual dissection, enabling a whole-parasite vaccine that provides sterilizing protection.

bioRxiv · Jun 22, 2020 · PreprintMicrobiology

Plasmodium PIMMS43 is required for ookinete evasion of the mosquito complement-like response and sporogonic development in the oocyst

V. Ukegbu, M. Giorgalli, S. Tapanelli, L. D. Rona, A. Jaye, C. Wyer, F. Angrisano, A. M. Blagborough, G. K. Christophides, D. Vlachou

This study identifies PIMMS43 as a key parasite protein enabling evasion of the mosquito complement-like response and sporogonic development, suggesting it as a target for malaria transmission-blocking interventions.

bioRxiv · May 31, 2019 · PreprintMicrobiology

Male-Specific Protein Disulphide Isomerase Function is Essential for Plasmodium Fertilization and Transmission

F. Angrisano, K. A. Sala, S. Tapanelli, G. K. Christophides, A. M. Blagborough

This study identifies a male-specific protein disulphide isomerase essential for Plasmodium fertilization and transmission, showing it as a viable target for malaria intervention.

bioRxiv · Sep 9, 2018Microbiology