Author

D. W. Granadier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. A. Evandy· 2 shared C. W. Smith· 2 shared K. Cooper· 2 shared K. S. Hopwo· 2 shared L. Iovino· 2 shared S. Kinsella· 2 shared A. Cardinale· 1 shared E. Velardi· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

C. A. Evandy

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Author profile →

2 papers

Recent·Most cited

Damage-induced pyroptosis drives endogenous thymic regeneration viainduction of Foxn1 by purinergic receptor activation

S. Kinsella, C. A. Evandy, K. Cooper, A. Cardinale, L. Iovino, P. deRoos, K. S. Hopwo, C. W. Smith, D. W. Granadier, L. B. Sullivan, E. Velardi, J. Dudakov

The paper identifies that damage-induced pyroptosis of thymocytes, mediated by purinergic receptor activation and Foxn1 upregulation, drives thymic regeneration after acute injury.

bioRxiv · Jan 19, 2023 · PreprintImmunology

Attenuation of homeostatic signaling from apoptotic thymocytes triggers a global regenerative response in the thymus

S. Kinsella, C. A. Evandy, K. Cooper, L. Iovino, P. C. deRoos, K. S. Hopwo, D. W. Granadier, C. W. Smith, S. Rafii, J. A. Dudakov

This study identifies a pathway involving NOD2 and miR29c that, when attenuated, triggers regenerative responses in the thymus after acute damage, enhancing T cell recovery.

bioRxiv · Aug 31, 2020 · PreprintImmunology