Author

C. W. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. A. Evandy· 2 shared D. W. Granadier· 2 shared K. Cooper· 2 shared K. S. Hopwo· 2 shared L. Iovino· 2 shared S. Kinsella· 2 shared A. Cardinale· 1 shared A. J. Barr· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

C. A. Evandy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Damage-induced pyroptosis drives endogenous thymic regeneration viainduction of Foxn1 by purinergic receptor activation

S. Kinsella, C. A. Evandy, K. Cooper, A. Cardinale, L. Iovino, P. deRoos, K. S. Hopwo, C. W. Smith, D. W. Granadier, L. B. Sullivan, E. Velardi, J. Dudakov

The paper identifies that damage-induced pyroptosis of thymocytes, mediated by purinergic receptor activation and Foxn1 upregulation, drives thymic regeneration after acute injury.

bioRxiv · Jan 19, 2023 · PreprintImmunology

Attenuation of homeostatic signaling from apoptotic thymocytes triggers a global regenerative response in the thymus

S. Kinsella, C. A. Evandy, K. Cooper, L. Iovino, P. C. deRoos, K. S. Hopwo, D. W. Granadier, C. W. Smith, S. Rafii, J. A. Dudakov

This study identifies a pathway involving NOD2 and miR29c that, when attenuated, triggers regenerative responses in the thymus after acute damage, enhancing T cell recovery.

bioRxiv · Aug 31, 2020 · PreprintImmunology

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

T. Vögtle, S. Sharma, J. Mori, Z. Nagy, D. Semeniak, M. J. Geer, C. W. Smith, J. Lane, S. Pollack, R. Lassila, A. Jouppila, A. J. Barr, D. J. Ogg, T. D. Howard, H. J. McMiken, , Y. A. Senis

This study identifies heparan sulfate as a critical regulator of G6b-B, showing it inhibits platelet and megakaryocyte function through Shp1/Shp2 signaling.

bioRxiv · Mar 25, 2019Biochemistry