Author

Dan McGuire

Nanostring Technologies (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

Joseph BeechemiD· 3 shared Evelyn MetzgeriD· 2 shared Michael J. Patrick· 2 shared Aaron Berliner· 1 shared Akua A. Agyemang· 1 shared Alicia AlonsoiD· 1 shared André F. RendeiroiD· 1 shared Anna Pascual ReguantiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Joseph BeechemORCID

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Author profile →

3 papers

Recent·Most cited

Tracing colorectal malignancy transformation from cell to tissue scale

Helena Lucia Crowell, Irene Ruano, Zedong Hu, Yourae Hong, Ginevra Caratù, Hubert H. Piessevaux, Ashley Heck, Rachel Liu, Max Walter, Megan Vandenberg, Kim Young, Dan McGuire, Evelyn Metzger, Margaret L. Hoang, Joseph Beechem, , Holger Heyn

This paper traces colorectal cancer progression by integrating spatial transcriptomics, single-nucleus RNA-sequencing, and histopathology to map cellular and molecular changes across tumor stages.

bioRxiv · Jun 23, 2025 · PreprintCancer Biology

The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs

Jiwoon Park, Roberto De Gregorio, Erika Hissong, Elif Ozcelik, Nicholas Bartelo, Felipe Segato Dezem, Luke Zhang, Maycon Marção, Hannah Chasteen, Yimin Zheng, Ernesto Abila, Junbum Kim, Theodore M. Nelson, Jacqueline Proszynski, Akua A. Agyemang, , Christopher E. Mason

SAHA creates a multimodal, subcellular-resolution reference atlas of healthy human tissues, revealing spatial organization and disease-associated disruptions across multiple organ systems.

bioRxiv · Jun 16, 2025 · PreprintSystems Biology

InSituCor: a toolkit for discovering non-trivial spatial correlations in spatial transcriptomics

Patrick J. Danaher, Dan McGuire, Michael J. Patrick, David Kroeppler, Haiyan Zhai, Joachim Schmid, Joseph Beechem

InSituCor identifies non-trivial spatial correlations in spatial transcriptomics data by filtering out correlations explained by cell type landscapes.

bioRxiv · Sep 19, 2023 · PreprintBioinformatics