Rachel Liu

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer

The paper integrates spatial morpho-transcriptomics to identify morphological subtypes in pancreatic cancer cell lines and tissues, linking them to gene expression, drug resistance, and metastatic potential.

Tracing colorectal malignancy transformation from cell to tissue scale

This paper traces colorectal cancer progression by integrating spatial transcriptomics, single-nucleus RNA-sequencing, and histopathology to map cellular and molecular changes across tumor stages.

Sub-cellular Imaging of the Entire Protein-Coding Human Transcriptome (18933-plex) on FFPE Tissue Using Spatial Molecular Imaging

This paper introduces a high-plex spatial molecular imaging technique capable of sub-cellular transcriptome analysis of FFPE tissues, achieving whole transcriptome coverage with high resolution and minimal dissociation bias.

Mycobacterium dormancy and antibiotic tolerance within the retinal pigment epithelium of ocular tuberculosis

This study investigates the metabolic mechanisms enabling Mycobacterium tuberculosis dormancy in retinal pigment epithelium cells and proposes a therapeutic strategy using phosphoenolpyruvate to enhance antibiotic efficacy.