Tracing LYVE1+ peritoneal fluid macrophages unveils two paths to resident macrophage repopulation with differing reliance on monocytes
Alexandre Gallerand, Jichang Han, Rachel L. Mintz, Jing Chen, Daniel D. Lee, Mandy M. Chan, Tyler T. Harmon, Xue Lin, Christopher G. Huckstep, Siling Du, Tiantian Liu, Jonathan Kipnis, Kory J. Lavine, Joel D. Schilling, Sharon Celeste Morley, , Gwendalyn J. Randolph
The paper identifies two distinct pathways for replenishing resident peritoneal macrophages after injury, with differing reliance on monocytes and intermediate stages.
bioRxiv · Mar 19, 2025 · PreprintImmunology