Author

Daniela Ortiz-Salazar

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Tyler S. BeyettiD· 2 shared Ilse K. Schaeffner· 1 shared Jaimin K. RanaiD· 1 shared Kristos I. Negrón TeróniD· 1 shared Lucy K. Robbie· 1 shared Michael J. EckiD· 1 shared Zeynep YurtseveriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

Tyler S. BeyettORCID

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2 papers

Recent·Most cited

Structural and Biochemical Analysis of the CABIT1 Domain of THEMIS

Kristos I. Negrón Terón, Daniela Ortiz-Salazar, Tyler S. Beyett

This study reports the crystal structure of the THEMIS CABIT1 domain and shows that LCK phosphorylation enables its interaction with SHP1 and protects SHP1 from ROS inhibition.

bioRxiv · Jul 21, 2026 · PreprintBiochemistry

Structure of the CABIT2 domain of THEMIS reveals a novel protein fold with an inserted SH3-like domain

Tyler S. Beyett, Zeynep Yurtsever, Ilse K. Schaeffner, Jaimin K. Rana, Lucy K. Robbie, Daniela Ortiz-Salazar, Michael J. Eck

The paper reports the crystal structure of the THEMIS CABIT2 domain, revealing a novel fold with an inserted SH3-like domain and insights into its interaction with GRB2.

bioRxiv · Oct 1, 2024 · PreprintBiochemistry