Metabolic engineering of Escherichia coli for optimized biosynthesis of nicotinamide mononucleotide, a noncanonical redox cofactor
William B. Black, Derek Aspacio, Danielle Bever, Edward J. King, Linyue Zhang, Han Li
This paper engineers Escherichia coli to biosynthesize nicotinamide mononucleotide (NMN+) for use in cell-free biosynthesis, achieving a 130-fold increase in intracellular NMN+ levels.
Microbial Cell Factories · Jul 27, 2020Peer-reviewedSynthetic Biology