Author

Linyue Zhang

University of California, IrvinePrimary ORCID profile (0000-0002-0623-4727 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Linyue ZhangiD1 paper · Sir Run Run Shaw Hospital

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:protein design· 1

Frequent Co-Authors

Edward J. King· 2 shared Han LiiD· 2 shared Danielle Bever· 1 shared Derek AspacioiD· 1 shared Jin Young KimiD· 1 shared Justin B. SiegeliD· 1 shared William B. BlackiD· 1 shared Youtian CuiiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersMolecular Biology

Edward J. King

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2 papers

Recent·Most cited

Engineering the key central metabolic enzyme to utilize a non-canonical redox cofactor

Jin Young Kim, Edward J. King, Youtian Cui, Linyue Zhang, Justin B. Siegel, Han Li

This paper engineers Escherichia coli GapA to use NMN+ instead of NAD+, achieving a high cofactor specificity switch through rational design and mutagenesis.

bioRxiv · May 28, 2025 · PreprintMolecular Biology

Metabolic engineering of Escherichia coli for optimized biosynthesis of nicotinamide mononucleotide, a noncanonical redox cofactor

William B. Black, Derek Aspacio, Danielle Bever, Edward J. King, Linyue Zhang, Han Li

This paper engineers Escherichia coli to biosynthesize nicotinamide mononucleotide (NMN+) for use in cell-free biosynthesis, achieving a 130-fold increase in intracellular NMN+ levels.

Microbial Cell Factories · Jul 27, 2020Peer-reviewedSynthetic Biology