Laboratory Validation of a Clinical Metagenomic Sequencing Assay for Pathogen Detection in Cerebrospinal Fluid
Steve A. Miller, Samia N. Naccache, Erik Samayoa, Kevin Messacar, Shaun Arevalo, Scot Federman, Doug Stryke, E Pham, Becky Fung, William J. Bolosky, Danielle Ingebrigtsen, Walter Lorizio, Sandra M. Paff, John A. D. Leake, Rick L. Pesano, , Charles Y. Chiu
The paper validates a clinical metagenomic sequencing assay for detecting pathogens in cerebrospinal fluid, showing 73% sensitivity and 99% specificity compared to clinical tests.
Genome Research · May 1, 2019Peer-reviewedGenomics