Author

Doug Stryke

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metagenomics· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Scot FedermaniD· 3 shared Charles Y Chiu· 2 shared Guixia Yu· 2 shared Sneha Somasekar· 2 shared Aaron S Burton· 1 shared Alex L Greninger· 1 shared Alexa B. R. McIntyreiD· 1 shared Becky Fung· 1 shared

Activity by Year

2015-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenomics

Scot FedermanORCID

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Author profile →

3 papers

Recent·Most cited

Laboratory Validation of a Clinical Metagenomic Sequencing Assay for Pathogen Detection in Cerebrospinal Fluid

Steve A. Miller, Samia N. Naccache, Erik Samayoa, Kevin Messacar, Shaun Arevalo, Scot Federman, Doug Stryke, E Pham, Becky Fung, William J. Bolosky, Danielle Ingebrigtsen, Walter Lorizio, Sandra M. Paff, John A. D. Leake, Rick L. Pesano, , Charles Y. Chiu

The paper validates a clinical metagenomic sequencing assay for detecting pathogens in cerebrospinal fluid, showing 73% sensitivity and 99% specificity compared to clinical tests.

Genome Research · May 1, 2019Peer-reviewedGenomics

Nanopore DNA Sequencing and Genome Assembly on the International Space Station

Sarah L Castro-Wallace, Charles Y Chiu, Kristen K John, Sarah E Stahl, Kathleen H Rubins, Alexa B. R. McIntyre, Jason P Dworkin, Mark L Lupisella, David J Smith, Douglas J Botkin, Timothy A Stephenson, Sissel Juul, Daniel J Turner, Fernando Izquierdo, Scot Federman, , Aaron S Burton

This study evaluates nanopore sequencing performance on the ISS, showing no performance decrease and successful genome assembly of bacterial and mammalian samples.

bioRxiv · Sep 27, 2016Genomics

Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

Alex L Greninger, Samia N Naccache, Scot Federman, Guixia Yu, Placide Mbala, Vanessa Bres, Jerome Bouquet, Doug Stryke, Sneha Somasekar, Jeffrey Linnen, Roger Dodd, Prime Mulembakani, Bradley Schneider, Jean-Jacques Muyembe, Susan Stramer, Charles Y Chiu

This study uses real-time nanopore sequencing and a new pipeline to rapidly detect viral pathogens in clinical samples with high accuracy.

Genome Medicine · Sep 29, 2015Peer-reviewedGenomics