Author

William J. Bolosky

Microsoft (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1 Assay:metagenomics· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Arun Karthi SubramaniyaniD· 1 shared Becky Fung· 1 shared Charles Y. ChiuiD· 1 shared Danielle Ingebrigtsen· 1 shared David A. PattersoniD· 1 shared Doug Stryke· 1 shared E Pham· 1 shared Erik Samayoa· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Arun Karthi SubramaniyanORCID

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2 papers

Recent·Most cited

Fuzzy set intersection based paired-end short-read alignment

William J. Bolosky, Arun Karthi Subramaniyan, Matei Zaharia, Ravi Pandya, Taylor Sittler, David A. Patterson

This paper introduces a new paired-end short-read alignment algorithm that uses fuzzy set intersection, achieving faster speed with comparable variant call concordance to existing methods.

bioRxiv · Nov 23, 2021 · PreprintBioinformatics

Laboratory Validation of a Clinical Metagenomic Sequencing Assay for Pathogen Detection in Cerebrospinal Fluid

Steve A. Miller, Samia N. Naccache, Erik Samayoa, Kevin Messacar, Shaun Arevalo, Scot Federman, Doug Stryke, E Pham, Becky Fung, William J. Bolosky, Danielle Ingebrigtsen, Walter Lorizio, Sandra M. Paff, John A. D. Leake, Rick L. Pesano, , Charles Y. Chiu

The paper validates a clinical metagenomic sequencing assay for detecting pathogens in cerebrospinal fluid, showing 73% sensitivity and 99% specificity compared to clinical tests.

Genome Research · May 1, 2019Peer-reviewedGenomics