Author

Dave A. Pai

BioNano Genomics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2 Organism:yeast· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Organism:human· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Cheryl M. Tucker· 2 shared Christopher G. DeSevo· 2 shared Maitreya J. DunhamiD· 2 shared Margaret L. Hoang· 2 shared Aaron W. MilleriD· 1 shared Anna B. Sunshine· 1 shared Bryony Lynch· 1 shared Caiti S. Smukowski Heil· 1 shared

Activity by Year

2016-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersEvolutionary Biology

Cheryl M. Tucker

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Author profile →

3 papers

Recent·Most cited

AmpliconReconstructor: Integrated analysis of NGS and optical mapping resolves the complex structures of focal amplifications in cancer

Jens Luebeck, Ceyda Çoruh, Siavash R. Dehkordi, Joshua T. Lange, Kristen M. Turner, Viraj Deshpande, Dave A. Pai, Chao Zhang, Utkrisht Rajkumar, Julie A. Law, Paul S. Mischel, Vineet Bafna

AmpliconReconstructor integrates optical mapping and NGS to resolve focal amplifications in cancer, revealing complex structures and origins of ecDNA and other rearrangements.

bioRxiv · Jan 22, 2020 · PreprintBioinformatics

Differential paralog divergence modulates evolutionary outcomes in yeast

Monica Rose Sanchez, Aaron W. Miller, Ivan Liachko, Anna B. Sunshine, Bryony Lynch, Mei Huang, Christopher G. DeSevo, Dave A. Pai, Cheryl M. Tucker, Margaret L. Hoang, Maitreya J. Dunham

This study shows that differential paralog divergence in yeast species leads to distinct evolutionary trajectories under sulfate limitation.

PLOS Genetics · Feb 14, 2017Peer-reviewedEvolutionary Biology

Selection on heterozygosity drives adaptation in intra- and interspecific hybrids

Caiti S. Smukowski Heil, Christopher G. DeSevo, Dave A. Pai, Cheryl M. Tucker, Margaret L. Hoang, Maitreya J. Dunham

This study shows that selection on heterozygosity drives adaptation in both intra- and interspecific yeast hybrids through loss of heterozygosity at the PHO84 gene.

bioRxiv · Sep 1, 2016Evolutionary Biology