Author

David Chambers

Friedrich-Alexander-Universität Erlangen-Nürnberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian WeichiD· 1 shared Carola BerkingiD· 1 shared Christopher LischeriD· 1 shared Cindy Flamann· 1 shared Gerhard KrönkeiD· 1 shared Heiko BrunsiD· 1 shared Johannes BergesiD· 1 shared Julio VeraiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Adrian WeichORCID

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1 paper

Recent·Most cited

The integration of network biology and pharmacophore modeling suggests repurposing Clindamycin as an inhibitor of pyroptosis via Caspase-1 blockage in tumor-associated macrophages

Adrian Weich, Johannes Berges, Cindy Flamann, Katrin Bitterer, Krishna Pal Singh, David Chambers, Christopher Lischer, Xin Lai, Olaf Wolkenhauer A, Carola Berking, Gerhard Krönke, Shailendra K. Gupta, Heiko Bruns, Julio Vera

The paper identifies Clindamycin as a potential inhibitor of pyroptosis in tumor-associated macrophages by integrating network biology and pharmacophore modeling.

Journal of Experimental & Clinical Cancer Research · Aug 4, 2025Peer-reviewedSystems Biology