UTX coordinates TCF1 and STAT3 to control progenitor CD8+ T cell fate in autoimmune diabetes
Ho-Chung Chen, Madison F. Bang, Hsing‐Hui Wang, Karl B. Shpargel, Lisa A. Kohn, David Sailer, S.C. Zhang, Ethan C. McCarthy, Maryamsadat Seyedsadr, Satchel Stevens, Caitlyn L. H. Pham, Zikang Zhou, Xihui Yin, Nicole M. Wilkinson, Esther Peluso, , Maureen A. Su
This study identifies UTX's role in regulating progenitor CD8+ T cell fate in T1D by interacting with TCF1 and STAT3, showing its importance in autoimmune diabetes progression.
Journal of Clinical Investigation · Dec 16, 2025Peer-reviewedImmunology