Author

Dehuan Wang

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hanyu RaoiD· 2 shared Ningyuan LiuiD· 2 shared Rebiguli Aji· 2 shared Wei‐Qiang GaoiD· 2 shared Wenxin Feng· 2 shared Yue Xu· 2 shared Guoning YuiD· 1 shared Jiahe LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCell Biology

Hanyu RaoORCID

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2 papers

Recent·Most cited

NSD2 deficiency disrupts the epigenetic landscape of cochlear hair cells to enhance ECM expression and to perturb cochlear hair cell function

Ziyi Wang, Yue Xu, Xiaojie Ma, Dehuan Wang, Wenxin Feng, Ningyuan Liu, Hanyu Rao, Wei Zhang, Rebiguli Aji, Ziwen Yu, Jiahe Li, Guoning Yu, Yazhi Xing, Wei‐Qiang Gao, Li Li

This study shows that NSD2 deficiency disrupts chromatin accessibility and gene expression in cochlear hair cells, leading to increased ECM expression and hearing impairment, which can be mitigated by ECM intervention.

bioRxiv · Sep 23, 2026 · PreprintCell Biology

Histone 3 lysine 36 trimethylation by SETD2 shapes an epigenetic landscape in intestinal stem cells to orchestrate lipid metabolism and prevent cell senescence.

Yue Xu, Ziyi Wang, Wenxin Feng, Hanyu Rao, Dehuan Wang, Wei Zhang, Rebiguli Aji, Ningyuan Liu, Wei‐Qiang Gao, Li Li

This study shows that H3K36me3, catalyzed by SETD2, maintains ISC stemness by regulating lipid metabolism and preventing senescence through chromatin remodeling and metabolic intervention.

bioRxiv · Apr 9, 2025 · PreprintCell Biology