Author

Denis Tkachuk

University Health Network

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Arvind Singh MeriD· 2 shared Benjamin Haibe‐KainsiD· 2 shared Christopher B. EelesiD· 2 shared Gangesh Beri· 2 shared Aline Fusco FaresiD· 1 shared Anna GoldenbergiD· 1 shared Anthony Mammoliti· 1 shared Catherine Adell O'BrieniD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Arvind Singh MerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PharmacoDB 2.0 : Improving scalability and transparency of in vitro pharmacogenomics analysis

Nikta Feizi, Sisira Kadambat Nair, Petr Smirnov, Gangesh Beri, Christopher B. Eeles, Parinaz Nasr Esfahani, Minoru Nakano, Denis Tkachuk, Anthony Mammoliti, Evgeniya Gorobets, Arvind Singh Mer, Eva Lin, Yihong Yu, Scott E. Martin, Marc A. Hafner, Benjamin Haibe‐Kains

PharmacoDB 2.0 enhances pharmacogenomics analysis by integrating new datasets, implementing FAIR pipelines, and improving drug response analysis tools.

Nucleic Acids Research · Oct 20, 2021Peer-reviewedBioinformatics

KuLGaP: A Selective Measure for Assessing Therapy Response in Patient-Derived Xenografts

Janosch Ortmann, Ladislav Rampášek, Elijah Tai, Arvind Singh Mer, Ruoshi Shi, Erin Stewart, Céline Mascaux, Aline Fusco Fares, Nhu‐An Pham, Gangesh Beri, Christopher B. Eeles, Denis Tkachuk, Chantal Ho, Shingo Sakashita, Jessica Weiss, , Anna Goldenberg

The paper introduces KuLGaP, a selective measure to assess therapy response in patient-derived xenografts by comparing treatment and control arms, improving accuracy over existing methods.

bioRxiv · Sep 8, 2020 · PreprintBioinformatics