Author

Christopher B. Eeles

University Health NetworkORCID 0000-0002-9962-7385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Arvind Singh MeriD· 3 shared Benjamin Haibe‐KainsiD· 3 shared Gangesh Beri· 3 shared Anthony Mammoliti· 2 shared Chantal Ho· 2 shared Denis Tkachuk· 2 shared Eva LiniD· 2 shared Marc A. HafneriD· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Arvind Singh MerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PharmacoDB 2.0 : Improving scalability and transparency of in vitro pharmacogenomics analysis

Nikta Feizi, Sisira Kadambat Nair, Petr Smirnov, Gangesh Beri, Christopher B. Eeles, Parinaz Nasr Esfahani, Minoru Nakano, Denis Tkachuk, Anthony Mammoliti, Evgeniya Gorobets, Arvind Singh Mer, Eva Lin, Yihong Yu, Scott E. Martin, Marc A. Hafner, Benjamin Haibe‐Kains

PharmacoDB 2.0 enhances pharmacogenomics analysis by integrating new datasets, implementing FAIR pipelines, and improving drug response analysis tools.

Nucleic Acids Research · Oct 20, 2021Peer-reviewedBioinformatics

Orchestrating and sharing large multimodal data for transparent and reproducible research

Anthony Mammoliti, Petr Smirnov, Minoru Nakano, Zhaleh Safikhani, Christopher B. Eeles, Heewon Seo, Sisira Kadambat Nair, Arvind Singh Mer, Ian Smith, Chantal Ho, Gangesh Beri, Rebecca L. Kusko, Massive Analysis Quality Control (MAQC) Society Board of Directors, Thakkar Shraddha, Susanna‐Assunta Sansone, , Benjamin Haibe‐Kains

The paper introduces a cloud-based platform called ORCESTRA for reproducible processing and sharing of multimodal biomedical data in a FAIR manner.

Nature Communications · Oct 4, 2021Peer-reviewedBioinformatics

KuLGaP: A Selective Measure for Assessing Therapy Response in Patient-Derived Xenografts

Janosch Ortmann, Ladislav Rampášek, Elijah Tai, Arvind Singh Mer, Ruoshi Shi, Erin Stewart, Céline Mascaux, Aline Fusco Fares, Nhu‐An Pham, Gangesh Beri, Christopher B. Eeles, Denis Tkachuk, Chantal Ho, Shingo Sakashita, Jessica Weiss, , Anna Goldenberg

The paper introduces KuLGaP, a selective measure to assess therapy response in patient-derived xenografts by comparing treatment and control arms, improving accuracy over existing methods.

bioRxiv · Sep 8, 2020 · PreprintBioinformatics