PhysiologyJournal of Clinical InvestigationPeer-reviewed
Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2
Matthew Wortham, Bastian Ramms, Chun Zeng…·Maike Sander
This study identifies SIRT2 as a regulator of β-cell proliferation, showing its role in controlling β-cell expansion during hyperglycemia while preserving feedback mechanisms.