Author

Derek P. Claxton

Primary ORCID profile (0000-0002-1374-7176 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Derek P. ClaxtoniD2 papers · Vanderbilt University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Craig Yoshioka· 1 shared Eric GouauxiD· 1 shared Hongtao ZhuiD· 1 shared Jie YuiD· 1 shared Nate Yoder· 1 shared Swastik PhuleraiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Craig Yoshioka

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1 paper

Recent·Most cited

Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2 heterotrimeric GABAA receptor in complex with GABA illuminates mechanism of receptor assembly and agonist binding

Swastik Phulera, Hongtao Zhu, Jie Yu, Derek P. Claxton, Nate Yoder, Craig Yoshioka, Eric Gouaux

The paper presents the cryo-EM structure of a triheteromeric GABAA receptor complexed with GABA, revealing mechanisms of receptor assembly and agonist binding.

bioRxiv · Jun 20, 2018 · PreprintBiophysics