Author

Jie Yu

Oregon Health & Science UniversityORCID 0000-0001-9227-038XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jie Yu6 papers · Chinese Academy of Sciences

Biology Disciplines

Click to filter author papers

Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Eric GouauxiD· 2 shared Hongtao ZhuiD· 2 shared Craig Yoshioka· 1 shared Derek P. Claxton· 1 shared Emad TajkhorshidiD· 1 shared Juan DuiD· 1 shared Lucia G. SivilottiiD· 1 shared Nate Yoder· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Eric GouauxORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeuroscienceCellPeer-reviewedFeb 1, 2021

Mechanism of gating and partial agonist action in the glycine receptor

Jie Yu, Hongtao Zhu, Remigijus Lapė…·Eric Gouaux

This study investigates the molecular mechanisms of partial agonist action and conformational transitions in the glycine receptor using electrophysiology, MD simulations, and cryo-EM.

145 citationstop 1%

experimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 20, 2018

Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2 heterotrimeric GABAA receptor in complex with GABA illuminates mechanism of receptor assembly and agonist binding

Swastik Phulera, Hongtao Zhu, Jie Yu…·Eric Gouaux

The paper presents the cryo-EM structure of a triheteromeric GABAA receptor complexed with GABA, revealing mechanisms of receptor assembly and agonist binding.

DOI 10.1101/337659

cryo-EMexperimental assay

𝕏 PostBluesky