A neuron-optimized CRISPR/dCas9 activation system for robust and specific gene regulation
Katherine E. Savell, Svitlana V. Bach, Morgan E. Zipperly, Jasmin S. Revanna, Nicholas A. Goska, Jennifer J. Tuscher, Corey G. Duke, Faraz A. Sultan, Julia N. Burke, Derek Williams, Lara Ianov, Jeremy J. Day
This paper develops a neuron-optimized CRISPRa system for efficient and specific gene regulation in neurons and the adult brain.
eNeuro · Jan 1, 2019Peer-reviewedNeuroscience