Katherine E. Savell

This study identifies Grin2c expression in mPFC neurons as a molecular component of cocaine-induced conditioned place preference engrams.

The paper shows that distinct prelimbic cortex ensembles encode response execution and inhibition during different phases of operant learning in rats.

The paper identifies a unique transcriptional signature in NAc neuronal ensembles activated during alcohol memory retrieval, showing their role in relapse and potential as therapeutic targets.

This study shows that amphetamine exposure in adolescence causes sex-specific changes in dopamine axon growth via Netrin-1/DCC signaling, with male mice showing increased vulnerability.

The paper identifies enhancer-gene regulatory links using eRNAs and shows their functional importance in neuronal systems.

This study identifies a dopamine-induced gene expression signature in the nucleus accumbens that drives cocaine-induced physiological and behavioral adaptations in rats.

This study shows blue light exposure alters gene expression in cultured neurons, but this effect is due to phototoxic interactions between light and culture media, not direct neuronal activation.

This paper develops a neuron-optimized CRISPRa system for efficient and specific gene regulation in neurons and the adult brain.