Author

Diana Pombal

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Ailsa L HartiD· 1 shared Aubin RamoniD· 1 shared Biao MaiD· 1 shared Daniele BiasciiD· 1 shared Emily Souster· 1 shared Eoin F. McKinneyiD· 1 shared Huimin WangiD· 1 shared J.C. Lee· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Ailsa L HartORCID

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2 papers

Recent·Most cited

Highly potent novel multi-armoured IL13Rα2 CAR-T subverts the immunosuppressive microenvironment of Glioblastoma

Maurizio Mangolini, Saket Srivastava, Emily Souster, Yajing Yang, Huimin Wang, Rajesh Karattil, Liam Schultz, Biao Ma, Diana Pombal, Matthew Greenig, Aubin Ramon, Pietro Sormanni, Shaun P Cordoba, Shimobi C. Onuoha

This paper develops a novel CAR-T cell therapy for glioblastoma that overcomes immunosuppression and improves persistence through a multi-armoured design.

bioRxiv · Jan 10, 2025 · PreprintCancer Biology

A blood-based prognostic biomarker in inflammatory bowel disease

Daniele Biasci, J.C. Lee, Nurulamin M Noor, Diana Pombal, Nina Ruth Lewis, Tariq Ahmad, Ailsa L Hart, Miles Parkes, Eoin F. McKinney, Paul Lyons, Kenneth G. C. Smith

This paper develops and validates a 17-gene qPCR classifier in whole blood that stratifies IBD patients into prognostic subgroups without requiring cell separation.

bioRxiv · Jan 30, 2019 · PreprintGenomics