Cancer BiologybioRxivPreprint
SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss
Xinqi Xi, Ling Liu, Natasha Tuano…·Joseph Rosenbluh
The paper identifies SRP19 as a vulnerability in cancers with APC loss, showing that reducing SRP19 inhibits proliferation through ER stress.
DOI 10.1101/2024.01.30.578083