Author

Dongbo Lu

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Afaf Helmy El-SagheeriD· 1 shared Andrew Marcel PregnalliD· 1 shared Anne‐Sophie WoznyiD· 1 shared Brian E. EckenrothiD· 1 shared Carel FijeniD· 1 shared Chelsea M. SmithiD· 1 shared Dale A. RamsdeniD· 1 shared Dennis A. SimpsoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Afaf Helmy El-SagheerORCID

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Author profile →

1 paper

Recent·Most cited

Hierarchical Coordination of Polymerase Theta and RAD51 Resolves Clustered Replication Fork Collapse

Chelsea M. Smith, Dennis A. Simpson, Paolo Guerra, Wanjuan Feng, Simon W. Ellington, Dongbo Lu, Carel Fijen, Natalie M. Boylston, Kishore Kumar CHIRUVELLA, Iman El‐Shiekh, Rachel Elizabeth Lee, Anne‐Sophie Wozny, Andrew Marcel Pregnall, Brian E. Eckenroth, Afaf Helmy El-Sagheer, , Gaorav P. Gupta

The paper shows Pol{theta} is recruited via RAD51 ubiquitylation to resolve clustered ICLs causing replication fork collapse in HR-proficient cells.

bioRxiv · Jul 2, 2025 · PreprintCell Biology