Origins and consequences of kinetoplast loss in trypanosomes
Melanie C. Ridgway, Douglas Escrivani, Markéta Novotná, Amy Wood, Michele Tinti, Achim C. Schnaufer, David Horn
This paper identifies mutations in the gamma subunit of the mitochondrial ATP synthase in Trypanosoma brucei that lead to kinetoplast loss and drug resistance.
bioRxiv · Dec 25, 2025 · PreprintMicrobiology