LL-37 modulates IL-17A/F-mediated airway inflammation by selectively suppressing Lipocalin-2.
Anthony Altieri, Dylan Lloyd, Padmanie Ramotar, Anne M. van der Does, Mahadevappa Hemshekhar, Neeloffer Mookherjee
This study shows LL-37 and its citrullinated form suppress IL-17A/F-induced LCN-2 production in bronchial epithelial cells, reducing neutrophil migration and airway inflammation.
Journal of Inflammation · May 23, 2025Peer-reviewedImmunology