Neeloffer Mookherjee

LL-37 and Citrullinated-LL-37 elicited Transcriptome and Cytokine Profiles in Human Bronchial Epithelial Cells: Citrullination dampens the inflammatory biosignature

This study compares the transcriptome and cytokine profiles of human bronchial epithelial cells stimulated with LL-37 and its citrullinated form, finding that citrullination reduces the inflammatory response.

LL-37 and citrullinated-LL-37 enhance disparate oxylipins: LL-37-mediated chemokine response is dependent on COX-2 and the P2X7 receptor in human bronchial epithelial cells

This study shows LL-37 enhances pro-inflammatory oxylipins and chemokines via COX-2 and P2X7 receptor, while citrullinated LL-37 reduces these effects.

LL-37 modulates IL-17A/F-mediated airway inflammation by selectively suppressing Lipocalin-2.

This study shows LL-37 and its citrullinated form suppress IL-17A/F-induced LCN-2 production in bronchial epithelial cells, reducing neutrophil migration and airway inflammation.

Proteomic Profiling of Hypoplastic Lungs Suggests an Underlying Inflammatory Response in the Pathogenesis of Abnormal Lung Development in Congenital Diaphragmatic Hernia

The paper uses proteomic profiling to identify inflammatory processes as a key factor in the pathogenesis of lung hypoplasia in congenital diaphragmatic hernia.

Integrating Proteomes for Lung Tissue and Lavage Reveals Pathways that Link Responses in Allergen-Challenged Mice

The paper integrates proteomes from lung tissue and BALF in allergen-challenged mice to identify compartment-specific and shared biological pathways involved in allergic asthma responses.